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To the Editor:—
An article, "Chlorothiazide (Diuril) as a Hyperuricacidemic Agent," appeared in The Journal (168:2128-2129 [Dec. 20] 1958). I have seen two patients with typical acute gout after the initiation of chlorothiazide therapy. The serum uric acid level in each was high. In each patient there have been no recurrences for 12 and 18 months, respectively, despite maintenance doses of the drug.
Kadish AH. GOUT AFTER DIURIL THERAPY. JAMA. 1959;169(5):526. doi:10.1001/jama.1959.03000220106026
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