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March 7, 1959

Cyclopropane Anesthesia

JAMA. 1959;169(10):1141-1142. doi:10.1001/jama.1959.03000270123027

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This edition comes 18 years after the first. The author believes that this is the time for another unified discussion of the subject since there is an apparent increase in the use of cyclopropane in clinical anesthesiology in the United States. This monograph is a reference work and should not be considered a clinical textbook. Its bibliography is extensive, containing 353 references. After a description of the physical and chemical properties and listing the concentrations of cyclopropane needed for anesthesia and respiratory arrest, 110 pages are devoted to its effect on the circulatory system. This is the most extensive discussion in the book and reviews the literature at length. Other chapters discuss the effects of cyclopropane on the respiratory and gastrointestinal systems, the blood, and other tissues. The chapter on clinical administration includes descriptions of techniques that have been reported in the literature.

The author chose to include a short

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