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March 7, 1959

Chloromycetin (Chloramphenicol)

JAMA. 1959;169(10):1142. doi:10.1001/jama.1959.03000270124028

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This book is the eighth in a series of monographs published under the direction of the editors of Antibiotics Annual. The authors have produced a highly readable and selective review of the important studies that have been made concerning chloramphenicol, the first of the broad-spectrum antibiotics. There are chapters on the history, activity, properties, dosage forms and route of administration, side-effects, and the clinical results obtained in various infections. Pertinent information is included on the use of other antibiotics and drugs in chloramphenicol-susceptible infections. There is an extensive bibliography and a subject index. As a whole, this monograph should give most readers a balanced picture of the place which chloramphenicol has come to occupy in the treatment of microbial diseases. It should also be of particular value as a reference to and source of information about the drug.

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