Two patients with signs and symptoms of chronic pulmonary disease were hospitalized because of the suspicion of tuberculosis. In one a lung biopsy specimen obtained at exploratory thoracotomy was found to contain lesions characteristic of pulmonary schistosomiasis, and ova of Schistosoma mansoni were identified. In the other the ova of S. mansoni were first found in the feces; later the characteristic ova were also found in pseudotubercules in specimens of lung tissue obtained by wedge biopsy. The first patient was treated with a total of 90 cc. of stibophen (Fuadin) injected intramuscularly over a period of 20 days, and the disease was arrested. The other improved after two courses consisting altogether of 95 cc. of stibophen; although he continued to complain of respiratory symptoms he returned to duty. Both had lived in Puerto Rico before entering the U. S. Army.
Richert JH, Krakaur RB. DIFFUSE PULMONARY SCHISTOSOMIASIS: REPORT OF TWO CASES PROVED BY LUNG BIOPSY. JAMA. 1959;169(12):1302–1306. doi:10.1001/jama.1959.03000290028007
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