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March 28, 1959


Author Affiliations

Jamaica, N. Y.

From the Arthritis Clinic and Department of Medicine, Queens General Hospital.

JAMA. 1959;169(13):1469-1470. doi:10.1001/jama.1959.73000300003012b

Rheumatoid arthritis has many visceral manifestations which serve to emphasize the systemic nature of the disease. Lesions have been reported in the nerves, muscles, heart, brain, eye, bones, gastrointestinal tract, pleura, lungs, and larynx.1 This paper presents the clinical and histological findings in a patient with a leg ulcer in rheumatoid artritis.

Report of a Case  A man, aged 52, was admitted to the Arthritis Clinic on Feb. 2, 1957, with a history of rheumatoid arthritis since 1946. He was thin and pale. The hip joints, right knee, ankles, and right elbow and wrists were swollen and tender. The adjacent muscles were conspicuously wasted. The proximal interphalangeal joints showed characteristic "spindling" deformities, and the fingers were deviated to the ulnar side. There was a poor response to therapy with gold salts, prednisone, prednisolone, and triamcinolone in large doses. Facial roundness was evident, and he had a palpable spleen. The