The course of tuberculosis was observed in a group of 22 pregnant women and compared with that in a group of 40 nonpregnant women of the same average age (23 years). The two groups were also similar in regard to the status of the disease. The progress of each patient was assessed in terms of rates of stabilization of the disease, of conversion of sputum and gastric washings, and of cavity closure. No significant difference between the two groups was discernible by any of these three criteria. There was no evidence that pregnancy affected the prognosis of tuberculosis provided the disease was treated the same in the pregnant as in the nonpregnant woman. The treatment consisted of certain combinations of isoniazid, streptomycin, and para-aminosalicylic acid. The obstetric results in the pregnant group were excellent; 21 had full-term, normal deliveries of healthy babies.
Flanagan P, Hensler NM. THE COURSE OF ACTIVE TUBERCULOSIS COMPLICATED BY PREGNANCY. JAMA. 1959;170(7):783–787. doi:10.1001/jama.1959.03010070023006
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