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Article
June 20, 1959

COMMUNITYWIDE VACCINATION PROGRAM WITH ATTENUATED POLIOVIRUS IN ANDES, COLOMBIA

Author Affiliations

Medellin, Colombia; Washington, D. C.

State Health Officer Antioquia, Colombia (Dr. Abad-Gómez), State Health Department, Antioquia, Colombia (Dr. Piedrahita), Department of Preventive Medicine and Public Health, School of Medicine, Medellín-Antioquia, Colombia (Dr. Solórzano), and Pan American Sanitary Bureau, World Health Organization (Dr. Martins da Silva).

JAMA. 1959;170(8):906-913. doi:10.1001/jama.1959.03010080014002
Abstract

An outbreak of paralytic poliomyelitis occurred in southern Antioquia, Colombia, in January, 1958. A census located 2,922 families who agreed to participate in a program of vaccination, and the immune status of the population was ascertained by systematic blood sampling. Oral vaccination with attenuated strains of poliovirus (types 1, 2, and 3) began in May, 1958. Comparison of prevaccination and postvaccination serums showed that, of the vaccinated children who lacked demonstrable antibody at the time of vaccination, 91 % responded to type 1 virus, 72% to type 2, and 87% to type 3. Both the safety and the immunizing efficacy of the three strains of virus employed were convincingly demonstrated.

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