This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
To the Editor:—
I read with interest the article, "Double-Blind Evaluation of Methylphenidate (Ritalin) Hydrochloride" by Darvill, in The Journal, April 11, page 1739, because I am conducting a study of this drug in outpatient psychiatric patients, as an adjuvant to psychotherapy. The patients take the drug only once weekly, just prior to the psychotherapeutic interview. To date, I have spent about eight months experimenting with the dosage and the effect of the drug on various patients at various times. I have recently begun a double-blind study.There are two important criticisms of the above article that I would make. Darvill makes no allowances for the wide variety of effect of this drug. In some of my patients the drug produced a very pleasant effect, as if they were on "cloud nine"; in an almost equal number it precipitated anxiety symptoms and caused a rebound depressive hangover. It would be
Rogers GA. EVALUATION OF METHYLPHENIDATE. JAMA. 1959;170(9):1108. doi:10.1001/jama.1959.03010090098024
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: