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July 25, 1959

The Physiopathology of Cancer

JAMA. 1959;170(13):1611. doi:10.1001/jama.1959.03010130115035

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The four parts of this book deal with the biology of cancer, the chemistry and physics of cancer, clinical investigations into the etiology and endocrinology of cancer, and some practical applications of the foregoing in chemotherapy, diagnostic exfoliative cytology, and radiation therapy. The amount of information presented is overwhelming, and the book is not one to be read continuously from cover to cover. Perhaps its size is a good omen, presaging a breakthrough in cancer research, for it reminds one of the large volumes on glycosuria and carbohydrate metabolism that reflected the unhappy state of diabetes research just before the discovery of insulin in 1922.

A few criticisms are offered as suggestions to prospective authors of similar works and to the present authors in case future editions are contemplated. The statistical formulas in this book are not always set up in a way that enables the reader to tell whether

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