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Article
August 1, 1959

CLINICAL EVALUATION OF SALINE SOLUTION THERAPY IN BURN SHOCK: II. COMPARISON OF PLASMA THERAPY WITH SALINE SOLUTION THERAPY

Author Affiliations

Lima, Peru

From the Hospital del Niño, Hospital Loayza, and Hospital Dos de Mayo. Dr. Markley is now with the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, U. S. Public Health Service, Department of Health, Education, and Welfare, Bethesda, Md.

JAMA. 1959;170(14):1633-1640. doi:10.1001/jama.1959.03010140013005
Abstract

In 79 burned adults, including 11 with burns of over 50%, treated with saline solution alone, there was no two-day mortality. In 74 other adults, including 14 with burns of over 50%, treated with plasma plus dextrose and water, there was a 12% two-day mortality. Selection of patients was made on a strictly alternating basis. In 73 burned children treated with saline solution alone, there was a 19% two-day mortality. In 92 other children treated with a combination of plasma and saline solution, there was only a 9% mortality. Saline solution therapy is considered good emergency therapy for adults, and addition of plasma to saline solution reduced the over-all acute mortality in children, particularly in the more severely burned.

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