[Skip to Content]
[Skip to Content Landing]
Article
August 29, 1959

RELATIONSHIP OF SIALIC ACID AND C-REACTIVE PROTEIN LEVELS IN HUMAN SERUM

Author Affiliations

Cincinnati

From the Institutum Divi Thomae and St. Mary's Hospital.

JAMA. 1959;170(18):2160-2162. doi:10.1001/jama.1959.03010180012005
Abstract

Total protein-bound sialic acid content was determined in normal and pathological human serum with special reference to the C-reactive protein test. Almost all of the serum positive for C-reactive protein had high sialic acid levels. It is likely that different pathological processes may account for the appearance of C-reactive protein and increase in the serum sialic acid level. Nevertheless, it is believed that determination of the level of serum sialic acid should prove a useful adjunct to the diagnosis of rheumatic fever and related diseases. The C-reactive protein itself did not contain sialic acid.

×