After a short course of therapy with ACTH in small doses, combined treatment with gold salts, phenylbutazone, and vitamin B12 effected a dramatic recovery within one week. During the next two months the patient remained asymptomatic and was able to return to a virtually normal diet, including fried foods, green vegetables, and fresh fruits. Roentgenograms of the colon three months after treatment showed marked improvement, with no evidence of marginal ulcerations. The combined treatment may be administered continuously for long periods without illeffects. The corticotropic hormone facilitated the control or bridged the initial severe phase.
Granirer LW. NEW TREATMENT FOR ULCERATIVE COLITIS: REPORT OF A FULMINATING CASE. JAMA. 1959;171(4):402–405. doi:10.1001/jama.1959.03010220026007
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