Previous reports of the possibility of using the electroencephalograph for the diagnosis of multiple pregnancies were confirmed in a study of 321 tracings obtained from 295 patients by means of an eight-channel instrument. The stage of pregnancy was an important factor in determining the success of the procedure; in the most favorable period, from the 20th through the 27th week of gestation, the diagnosis of multiple gestations was made without a single error. The earliest positive diagnosis of twins was made at 16 weeks, and an accurate diagnosis of triplets at 20 weeks. Early recognition of multiple pregnancies is important. The convenience and safety of the electroencephalograph make it desirable that this instrument be used more widely for this purpose in obstetrics.
Novotny CA, Hass WK, Callagan DA. EARLY DIAGNOSIS OF MULTIPLE PREGNANCY: USE OF ELECTROENCEPHALOGRAPH IN PRENATAL EXAMINATION. JAMA. 1959;171(7):880–884. doi:10.1001/jama.1959.03010250018005
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