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Article
October 24, 1959

DDT: The Insecticide Dichlorodiphenyltrichloroethane and Its Significance

JAMA. 1959;171(8):1160. doi:10.1001/jama.1959.03010260116027

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Abstract

This second of a three-volume series on DDT is devoted to the significance of the insecticide in human and veterinary medicine. It presents an exhaustive array of material on the pharmacology and toxicology of DDT and its medical contribution through the control of insect vectors. Part 1 of this volume is devoted to a detailed review of the basic pharmacology of DDT, its toxicity for man on the basis of experimental exposure and use, and the practical problems involved in the hazards of DDT to man and useful animals.

Part 2 contains chapters discussing the hygienic, economic, and social benefits of DDT to mankind. The problem of the resistance to DDT among arthropods of public health importance, types and mechanisms of resistance, and the significance and future outlook of resistance are considered in this section. The author stresses that, irrespective of the resistance problem, DDT and other chlorinated hydrocarbon insecticides,

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