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November 7, 1959


Author Affiliations

Atlanta, Ga.

From the Department of Ophthalmology, Emory University School of Medicine; the Grady Clay Eye Clinic, Grady Memorial Hospital; Atlanta; and the Communicable Disease Center, Public Health Service, U. S. Department of Health, Education, and Welfare.

JAMA. 1959;171(10):1339-1341. doi:10.1001/jama.1959.73010280003015a

A patient with superficial punctate keratitis, who was receiving antibiotic and steroid therapy, developed an indolent corneal ulcer due to Candida parapsilosis (C. parakrusei). Treatment, which included use of the antifungal antibiotics nystatin (Mycostatin) and amphotericin B (Fungizone), was followed by slow healing of the ulcer.

Report of a Case  The patient was first seen on Oct. 26, 1956, at the age of 37 years. She gave a history of five-year chronic recurrent inflammation of first one eye and then the other. Examination revealed a superficial punctate keratitis of the left eye. The vision was 20/20 in the right eye and only 2/200 in the left. The left eye was amblyopic due to esotropia in childhood. A litmus paper test revealed only 5 mm. of paper to be moist in the right side and only 6 mm. on the left after five minutes. The patient was thought to have keratitis