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To the Editor:—
I have read with interest the paper on the relationship of hyperuricemia to hypercholesteremia and acute myocardial infarction by Kohn and Prozan (J. A. M. A.170:1909-1912 [Aug. 15] 1959). The authors implied that the hyperuricemia seen in their patients was a hereditary defect and gave no information as to other possible causes of hyperuricemia in this group. Hyperuricemia may be due to several causes other than heredity. The most common is chronic renal insufficiency. It would be of great interest to learn the frequency of blood urea nitrogen elevation among the 50 patients reported on in this paper. Also information should be given as to the possible presence of blood dyscrasias that are associated with hyperuricemia (Talbott: Medicine38:173 [May] 1959; Gutman: Ann. Int. Med.39:1062 [Nov.] 1953). Finally, in a group of patients with acute myocardial infarction, it is possible that some
Wallace SL. HYPERURICEMIA. JAMA. 1959;171(10):1401. doi:10.1001/jama.1959.03010280125031
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