Giant pigmented nevi afflict the patient not only with an unsightly cosmetic defect but also with the hazard of possible conversion to cancer. Such a nevus, extending over the back of an 18-year-old girl, was removed by surgical excision. Several hundred smaller nevi were removed from other parts of her body surface. Three separate operative procedures were required; the first was to remove the nevi from the right side of her body and prepare a skin donor site, the second to remove part of the large nevus and the smaller ones from her left side, and a third for complete excision of the giant nevus. Almost all the skin grafts were successful, and no malignant changes were found in any of the nevi excised.
Russell JL, Reyes RG. GIANT PIGMENTED NEVI. JAMA. 1959;171(15):2083–2086. doi:10.1001/jama.1959.03010330045012
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