The relative value of various diagnostic findings and of various types of treatment were studied in 510 patients with testicular tumors. The average age of the patients was 27.0 years. In 26 cases the tumor appeared in a cryptorchid, and in 6 of these orchiopexy had been done. Symptoms were varied and misleading, and the onset was often insidious. Metastases to bones were exceedingly rare. The Ascheim-Zondek test, when results were positive, indicated spread and was a fairly reliable guide to prognosis. Of 389 patients, treated by various combinations of therapy and successfully followed up, 204 survived more than five years. In cases of choriocarcinoma, neither lymphadenectomy nor irradiation appeared to alter the course of the disease. In cases of seminoma, orchiectomy followed by irradiation is recommended; in cases of embryonal carcinoma and teratocarcinoma, in the absence of clinical metastases, it is recommended that orchiectomy be followed by bilateral lymphadenectomy through a transabdominal approach.
Patton JF, Hewitt CB, Mallis N. DIAGNOSIS AND TREATMENT OF TUMORS OF THE TESTIS. JAMA. 1959;171(16):2194–2198. doi:10.1001/jama.1959.03010340038009
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