To the Editor:—
I have read the article "Dihydrostreptomycin Deafness" in The Journal, Aug. 1, page 1657, reporting 32 cases of deafness occurring after the administration of dihydrostreptomycin or products containing this substance associated with other antibiotics. I should like to mention the possibility of the reduction of dihydrostreptomycin ototoxicity by the addition of pantothenic acid or sodium pantothenate. In this way we can employ the beneficial action of dihydrostreptomycin, especially in tuberculosis. Some bibliographic references are included.
Dutrem W. DIHYDROSTREPTOMYCIN OTOTOXICITY. JAMA. 1959;171(17):2355. doi:10.1001/jama.1959.03010350077021
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