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February 13, 1960

The Acute Radiation Syndrome: A Medical Report on the Y-12 Accident, June 16, 1958

JAMA. 1960;172(7):763. doi:10.1001/jama.1960.03020070121035

In a series of 13 laboratory and clinical studies made on five persons who were accidentally exposed to whole body radiation of large doses of radiation at Oak Ridge, Tenn., additional information concerning the clinical, hematological, and biochemical changes after exposure is described in detail. The five persons, each exposed to 200 to 300 rads, were hospitalized immediately. Extensive studies were begun at once and continued until the patients were discharged. Three additional persons who received doses of 70 to 20 rads were similarly studied as outpatients.

A record of the profile of residual radioactivity from the feet to the top of the head of each patient was made with a linear scanner. Recordings reflected the general distribution of radioactivity, presumably sodium-24, throughout the body. The tracings resembled the profile of the supine human body. The method permitted determination of relative amounts of remaining radioactivity and, by comparison of the

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