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March 5, 1960


JAMA. 1960;172(10):1084-1085. doi:10.1001/jama.1960.03020100092025

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To the Editor:  My experience, the experience of my practicing physician friends, and the records at Eli Lilly and Company strongly suggest that allergic reactions to the penicillin in poliomyelitis vaccine are extremely infrequent. It was believed important to express this view in print because the contrary one has been published by certain authors, including Zimmerman (J. A. M. A.167:1807 [Aug. 9] 1958).Zimmerman is right when he says that, from the data available to the company, the incidence of reactions cannot be computed, and this point was stressed in the summary of my article: "Because of incomplete reporting, the data do not allow an estimate of the incidence of reactions." It may also be said that the data presented in Zimmerman's article do not allow an estimate of the incidence of reactions, yet he states that "six cases from private practice between May and November, 1957, indicate

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