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July 7, 1962

Active Tetanus Immunization

Author Affiliations

375 South St., Jamaica Plain 30, Mass.

JAMA. 1962;181(1):62. doi:10.1001/jama.1962.03050270064016

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To the Editor:—  The paper on "Delayed Recall of Active Tetanus Immunization" by Kaiser et al. (JAMA178:914 [Dec. 2] 1961) presents a praiseworthy attempt to find out whether or not the interval since the last previous inoculation of tetanus toxoid is related to the speed of response to a booster dose. The authors compared their own study on patients who had gone 14 to 18 years since their last tetanus toxoid inoculation with a paper by Turner, Stafford, and Goldman in which the intervals were 5 to 11 years, and a study by Banton and Miller in which 1 to 5 years had elapsed (but not with the 60 subjects similarly studied by Schlegel, Helv Chir Acta18:378, 1951). Unfortunately, the criterion of a response to the booster dose which Kaiser et al. employ is one proposed 20 years ago by Miller, Ryan, and Beard by which

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