Throat swabbings were taken weekly and cultured for groupable beta-hemolytic streptococci from September, 1960, through May, 1961, from 260 children in the first 6 grades of all schools in Bismarck. None of the children followed developed rheumatic fever or glomerulonephritis. One new case of rheumatic fever occurred during the study making an incidence of 0.0037% for the entire city. There was no significant seasonal variation in the weekly group A streptococcal prevalence rates. The average group A prevalence rate for the entire study was 16.6%, and the range in the weekly rates was 12%-21%. Group A streptococci were not isolated in a random pattern from these children. Of the 260 children followed 146 were found to have group A at least once during the study, and 35 children contributed over half of the cultures positive for group A.
Nicholas WC, Steele CP. Occurrence of Groupable Beta-Hemolytic Streptococci: Study Among School Children in Bismarck, N.D. JAMA. 1962;181(3):197–205. doi:10.1001/jama.1962.03050290019004
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