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April 9, 1960


JAMA. 1960;172(15):1679-1680. doi:10.1001/jama.1960.03020150103030

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To the Editor:—  In The Journal, Jan. 16, 1960, page 229, the author of the article entitled "Treatment of Superficial Thrombophlebitis with Phenylbutazone" presented his results as follows: "I had occasion to treat 25 patients with thrombophlebitis at the U. S. Army Hospital, Fort Sill, Okla., in 1956 and 1957 and about 15 patients in private practice since that time. All patients responded promptly to short courses of phenylbutazone therapy, and no side-effects from the drug were observed in any. Three of the more difficult cases are presented."He then proceeded to report briefly on three patients, all of whom appear to have had deep thrombophlebitis (all three had edema), in spite of the title of the article.There are two main points about which I would like to take issue. First, the paragraph quoted above along with the case reports leads one to believe that some 40 patients with

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