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August 25, 1962

Biophysics of Physiological and Pharmacological Actions: Papers Presented at New York Meeting of the American Association for the Advancement of Science, December 26-28, 1960

JAMA. 1962;181(8):734. doi:10.1001/jama.1962.03050340072024

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This volume consists of 30 papers which were presented in December, 1960, at a symposium sponsored jointly by the American Association for the Advancement of Science, the American Physiological Society, and the Society of General Physiologists. Primary emphasis is given to current concepts of the electrical and ionic events associated with nerve and muscle excitability. Active transport and membrane selectivity in elementary systems such as red blood cells are discussed first; the more complex problems presented by nerves, voluntary striated muscle, cardiac muscle, and smooth muscle are then dealt with successively. Junctional transmission and the contractile mechanism in muscle receive special attention and the probable energy supply for the various activity processes is discussed. The mechanism of action of certain pharmacologic agents is considered in terms of their effect on membranes. Numerous models, conceived in the light of recent experimental data, are presented. Throughout, the illustrations are of good quality.

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