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September 8, 1962

The Role of Dexpanthenol in Postoperative Ileus

Author Affiliations

From the departments of surgery and hospital pharmacy, Roswell Park Memorial Institute.

JAMA. 1962;181(10):827-830. doi:10.1001/jama.1962.03050360013003

The effectiveness of dexpanthenol in preventing and treating postoperative ileus was tested in observations on 101 patients who underwent major surgery under general anesthesia. The test group of 50 patients who received dexpanthenol was compared with a contratest group who received sodium chloride. No significant difference was found between the 2 groups as to incidence of postoperative complications, duration of hospitalization, or other criteria of gastrointestinal function.