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November 26, 1960


JAMA. 1960;174(13):1731-1732. doi:10.1001/jama.1960.03030130059018

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Our knowledge of cancer of the male breast is important not only because of the disease itself, but more especially because its comparison with the disease in the female may help our understanding of the latter. This comparison is of particular interest because of their apparent hormonal differences.

Several hundred cases of male breast cancer have been reported with similar general conclusions as to the characteristics of the lesion. Less than 1% of all breast cancers occur in men. The disease in men and women is similar in the following respects: the average age of discovery is about 56 years; about 2 1/2% of cancers are bilateral; and no significant history of trauma is generally found. Histologically, infiltrating duct carcinoma is much the most common finding. Although a painless mass is the most frequent initial symptom in both male and female, the presence of a discharge from the nipple is

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