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December 10, 1960


JAMA. 1960;174(15):1967. doi:10.1001/jama.1960.03030150055015

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Wilms's tumor continues to be one of the most common and most devastating malignant tumors of childhood. This tumor is discussed in the current issue of The Journal, p. 1925. The role of the general practitioner and pediatrician is of prime importance in the discovery of this neoplasm. Frequently it is the parent who first notices an abdominal mass, but many times it is the family physician or pediatrician who, on routine physical examination, discovers the abnormality. The palpation of such a mass in a child implicates a number of possibilities. The differential diagnosis would most commonly include neuroblastoma, hydronephrosis, unilateral multicystic kidney, and hepatoma.

Although some progress has been made in the treatment of Wilms's tumor, the unfortunate patient who harbors this neoplasm still has a relatively poor prognosis. Most frequently the patient is a child three years old or less. The tumor occurs less frequently in older children

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