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September 15, 1962

Infantile Disseminated Histoplasmosis: A Case Reporting Pillow Feathers as a Source of Infection

Author Affiliations

Bethesda, Md.; Washington, D.C; Bethesda, Md.

JAMA. 1962;181(11):999-1000. doi:10.1001/jama.1962.03050370067017c

SINCE THE INITIAL report by Dodd and Tompkins of infantile disseminated histoplasmosis, several other cases have been recorded. The source of infection was unknown in these patients. This is in contrast to the experience in adults in whom the source of infection is commonly soil contaminated with Histoplasma capsulatum. It is our purpose to report a case of severe disseminated histoplasmosis in an infant from whose pillow feathers H. capsulatum was cultured.

Report of a Case

The patient, a male, was born Nov. 2, 1960, weighing 5 lb. and 11 oz. (2.6 kg.). Gestation had been terminated by induction of labor in the eighth month because of erythroblastosis fetalis. He became severely icteric during the first day of life and was successfully treated with 3 exchange transfusions. After 2 weeks he was discharged from the nursery in good condition. He appeared to be thriving until February, 1961, when fever developed