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September 15, 1962

In Situ Ductal Carcinoma of the Breast

Author Affiliations

Los Angeles

JAMA. 1962;181(11):1000-1001. doi:10.1001/jama.1962.03050370068017d

IN RECENT LITERATURE emanating from the Mayo Clinio, a study of preinvasive duct carcinoma of the breast was presented. This article is being written to add to the total number of cases in the literature of this rarely found condition, to offer what we consider to be an important presenting symritom, and to plead for more attention to symptoms of pain and to meticulous breast examination in order to discover carcinoma in its preinvasive stage.

Unlike carcinoma of the cervix, we do not have a laboratory method devised to detect jireinvasive carcinoma of the breast; hence, we must depend on a high index of suspicion in our examination of the breast after carefully noting the presenting symptoms of the patient.

History It is generally conceded that carcinoma of the breast takes origin from either ducts or lobules. It is the degree of anaplasia and infiltration of the stroma which determines