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March 25, 1961

Interphalangeal Osteoarthritis: Characterized by Painful, Inflammatory Episodes Resulting in Deformity of the Proximal and Distal Articulations

JAMA. 1961;175(12):1049-1053. doi:10.1001/jama.1961.03040120011003

A form of osteoarthritis localized in the interphalangeal articulations of the fingers and characterized by acute inflammatory episodes with eventual ankylosis of some joints is described. Clinical features of the condition, as summarized from the author's 23 cases, indicate that it occurs predominantly in middle-aged women, tends to be hereditary, and is frequently accompanied by osteoarthritic changes in the cervical vertebrae. The acute episodes often suggest rheumatoid arthritis, but the disease does not affect other peripheral articulations, and the serologic test for rheumatoid factor is negative. Treatment is unsatisfactory, although symptomatic relief is obtained from intra-articular hydrocortisone injections.