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September 29, 1962

Calcified Intrahepatic Métastases from Carcinoma of the Breast

Author Affiliations

New Hyde Park, N.Y.

JAMA. 1962;181(13):1139-1140. doi:10.1001/jama.1962.03050390041012c

INTRAHEPATIC CALCIFICATION occurs in association with a variety of diseases such as hepatomas, cavernous hemangiomas, intrahepatic calculi, hepatic infections or granulomas, and parasitic infestations such as echinococus cysts. Liver metastases from malignant diseases which may calcify are mainly from neuroblastomas or carcinomas of the sigmoid.

The present report concerns a patient with numerous heavily calcified liver metastases from a primary breast carcinoma.

Report of a Case

A 38-year-old woman was admitted because of a tumor in the upper outer quadrant of her right breast.A frozensection diagnosis of cancer was made and a radical mastectomy was performed for an infiltrating ductal carcinoma.

There was no demonstrable extension into the lymph nodes. Postoperative radiation therapy was not given.

The patient remained asymptomatic for 28 months. She was then readmitted because of pain in both lower extremities. Her liver was not palpable at this time. X-ray examination of the pelvis revealed lytic métastases