Electrodiagnostic testing in neuromuscular disease has been described. The chronaxy determination is a stimulating test which should be done routinely in neuromuscular testing. It is a gross test, but it is very useful in determining the presence of denervation. Electromyography is a recording test and is more sensitive than a chronaxy determination. Electromyography can help in the diagnosis of lower motor neurone disease and in myopathic disease, because the findings in these are characteristic. Nerve conduction velocity determination is a stimulating and recording test. With it one can differentiate anterior horn cell disease from disease of the axone. One can also localize nerve compression when this condition is present.
Rosenthal AM. Electrodiagnostic Testing In Neuromuscular Disease. JAMA. 1961;177(12):829–833. doi:10.1001/jama.1961.03040380007002
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