[Skip to Content]
[Skip to Content Landing]
Other Articles
October 7, 1961

Control of Neoplastic Effusions

Author Affiliations

1450 Broadway, New York City

JAMA. 1961;178(1):91. doi:10.1001/jama.1961.03040400093027

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To the Editor:—  In The Journal (176:747 [May 27] 1961) there is a question concerning new treatments for metastatic carcinoma of the pleura. I do not question the validity of the reply, but I believe it might have been desirable to mention the possible use of quinacrine ( Atabrine) hydrochloride in the control of neoplastic effusions. This has been reported by Gellhorn, et al. (Dis Chest39:165-176 [Feb.] 1961).While the number of cases reported has been relatively small, it does appear that quinacrine is effective in controlling neoplastic effusions and while its use is not unattended by side reactions, the drug has the advantage of lack of toxicity to the blood forming organs and does not involve the hazards of the radioactive isotopes.

First Page Preview View Large
First page PDF preview
First page PDF preview