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December 9, 1961

Intra-Uterine Myocardial Infarction

JAMA. 1961;178(10):1039-1040. doi:10.1001/jama.1961.73040490029015c

MYOCARDIAL infarction in the newborn is a rare event. Ravich and Rosenblatt reported 2 cases in 1947.1 Subsequent reports have related such neonatal infarcts to an aberrant origin or other abnormalities of the coronary arteries such as medial calcific sclerosis, focal intimal proliferation, or subintimal fibrosis.2-6 Most of these coronary lesions presumably develop during fetal life, and yet only one report has appeared of myocardial infarction in utero.2 The current report records a second case of myocardial infarction in utero. The coronary arterial lesion proved of particular interest because of its similarity to lesions sometimes seen in adult coronary arterial disease.

Report of a Case  A 24-year-old, RH negative, gravida 2, para 1, white female was delivered of a 7 lb., 10 oz. (3,458.6 gm.) female following a pregnancy complicated only by a 36-lb. (18 kg.) weight gain. Labor was oxytocin (Pitocin) induced and lasted 4½ hours.