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October 6, 1962

New Antibiotic For Gonorrhea

JAMA. 1962;182(1):A32. doi:10.1001/jama.1962.03050400112045

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Abstract

A British physician said a new antibiotic, actinospectacin, may be the answer to "deteriorating results" in the treatment of gonorrhea. Dr. R. R. Willcox of St. Mary's Hospital in London, said that in many areas of the world, gonorrhea is "largely uncontrolled and the numbers of new cases are rising each year—in some places alarmingly."

Growing failure rates in the treatment of the disease with penicillin and streptomycin are an important reason for the increased incidence of gonorrhea, according to Dr. Willcox.

He reported on results of treating 1,794 male patients with penicillin or streptomycin by single injection. Both drugs showed deterioration of results with the years, but "in respect to penicillin, some improvement has recently been noted following a change of treatment practices."

In another series of 1,036 cases, Willcox said that "reasonably satisfactory cure rates" were obtained with oral doses of penicillin and other antibiotics. This treatment, however,

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