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April 10, 1967


JAMA. 1967;200(2):163-164. doi:10.1001/jama.1967.03120150119029

A recent communication described physical inactivity as a "lethal factor in myocardial infarction among men." The conclusions obtained from this study by Frank and associates1 represent another addition to the growing list of reports which describe a relationship between exercise and heart disease. The data in this report were obtained from a study of 301 men who suffered an initial myocardial infarction. The incidence of first infarctions among the least active group was approximately one and one-half times that found in the most active subjects. However, the most dramatic finding was that the mortality in the least active category in the four weeks after diagnosis of acute infarction was three times that noted in the group of most active men and twice that for the intermediate activity classification. Many investigators have assessed only job-connected physical activity; this approach neglects potentially important nonoccupational exercise. Cognizant of this factor, Frank et al