CLONORCHIASIS is endemic in China, Korea, Japan, and Formosa. San Francisco, being a strategic center in commerce with the Far East, probably has the largest colony of patients with clonorchiasis outside the Orient. This study describes factors pertinent to an understanding of the disease in an extra-Oriental setting.
History.—On Sept. 9, 1874, McConnell in Calcutta performed an autopsy on a Chinese man and discovered that the bile ducts were swarming with live flukes. His report in 1875 is the first describing the disease in humans. In 1888 Biggs, who was pathologist at New York's Bellevue Hospital, had a similar experience and discovered the first case of clonorchiasis in the United States. The disease was recognized in San Francisco in 1901 when White found flukes in 18 Chinese dead of plague. The flukes have a tenacious hold on life, and when found at postmortem examination are usually alive. But White found
Strauss WG. Clonorchiasis in San Francisco. JAMA. 1962;179(4):290–292. doi:10.1001/jama.1962.03050040044013a
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