[Skip to Content]
[Skip to Content Landing]
Other Articles
February 3, 1962

The Child with Diabetes Mellitus

Author Affiliations

615 Williams Ave., Brooklyn 7, N.Y.

JAMA. 1962;179(5):386. doi:10.1001/jama.1962.03050050076019

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To the Editor:—  In the article in The Journal (176:854 [June 10] 1961), entitled, "The Child with Diabetes Mellitus," Dr. R. L. Jackson thoroughly discusses diabetic acidosis in children. However, he fails to discuss protein metabolism in this condition.The genesis of diabetic acidosis results in the rapid depletion of the glycogen stores of the liver and muscle. As a consequence, tissue protein is rapidly broken down in an apparently hopeless attempt to furnish antiketogenic fuel, and urinary nitrogen reaches enormous figures.Protein cannot be stored dry, for it retains with it 3 or more parts of water. Thus, the loss of 1 lb. of body protein will result in a concomitant loss of 3 lb. of water and a weight loss of 4 lb. The loss of this water in no way affects the water balance of the body.The author states, "Inasmuch as the patient has a

First Page Preview View Large
First page PDF preview
First page PDF preview