In 2 children, presented because of involuntary movements, the diagnoses of rheumatic chorea, dystonia musculorum deformans, and encephalitis were entertained before roentgenologic signs of expanding cerebral lesions were demonstrated. A 6-year-old boy developed chorea in the left arm 4 months after an attack of scarlet fever. The movement disorder progressed and later involved the left leg and right arm. The diagnosis of an astrocytoma in the right thalamus was made at craniotomy performed 14 months after the onset of symptoms. A 12-year-old girl began to limp shortly after recovery from a respiratory infection. The dystonia progressed, and signs of focal involvement of cranial nerves and corticospinal tracts appeared. A franctional pneumoencephalogram ultimately revealed a mass in the upper part of the pons and midbrain.
Millichap JG, Miller RH, Backus RE. Intracranial Tumors in Childhood: Manifestation as Chorea and Other Involuntary Movements. JAMA. 1962;179(8):589–593. doi:10.1001/jama.1962.03050080001001
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