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May 8, 1967


JAMA. 1967;200(6):19-34. doi:10.1001/jama.1967.03120190011003

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First Human Prostate Scans Reported  The first successful, in vivo scans of the human prostate have been accomplished at Walter Reed General Hospital with the use of a short-lived isotope.Prostate glands of 8 patients were visualized using69mzinc, in either citrate or chloride solution, according to Lt Col Gerald S. Johnston, MC, USA."Although we are not yet satisfied with the solution used, the prospects are good for visualizing primary lesions, metastases, and doing prostatic physiology studies," Col Johnston told JAMAMedical News.The tracer material used, produced at Oak Ridge National Laboratory, has a half-life of 13.8 hours. The isotope must be flown rapidly from Tennessee to Washington, DC. This has been accomplished three times since the end of January.Zinc localizes preferentially in prostate and liver, explained Col Johnston, who is chief of the Walter Reed radioisotope section. After intravenous injection,69mZn appears rapidly