Selection of antimicrobial agents for a patient with an infection must usually be made before the actual sensitivity pattern of that organism is available from the laboratory. In the described system, accurate statistical information is kept by the use of optical coincidence cards of all previous bacterial sensitivities as studied in that laboratory. By sorting for immediately available information (source of specimen, Gram stain, and morphology), a prediction is obtained for this organism. This prediction is based on current experience in this laboratory and reflects changes in prevailing sensitivity patterns on a short-term basis. Ideal combinations of antibiotics may be obtained by special sorting procedures.
Gantner GE, Laskowski LF. Antibiotic Selection Based Upon Immediately Available Data: Prediction of Sensitivities From Source, Gram Stain, and Morphology. JAMA. 1967;200(6):431–434. doi:10.1001/jama.1967.03120190057006
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