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March 17, 1962

Acute Pancreatitis and Steroid Therapy

Author Affiliations

320 Hawley Ave., Bridgeport 6, Conn.

JAMA. 1962;179(11):916. doi:10.1001/jama.1962.03050110084028

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To the Editor:—  I was one of the earlier authors ( Eskwith, Cacace, and Sollosy, Acute Hemorrhagic Pancreatitis Treatment with Cortisone, New Engl J Med252:494,1955) who reported on the therapy of acute pancreatitis with cortisone. There are several commments I should like to make on the editorial "Acute Pancreatitis and Steroid Therapy" that appeared in the Dec. 9, 1961, issue of The Journal (178:1005).It is not my opinion that the steroids' principal use is in combating vascular collapse in this disease. In the original and subsequent cases I have treated, rapid relief of pain and abdominal tenderness, and quick defervescence have been equally striking features of this form of treatment.Carone and Liebow's findings of small areas of pancreatic necrosis in patients treated with steroids is an interesting pathological finding, but none of these patients experienced symptoms of pancreatitis. Nelp's finding that long-term steroid therapy of any

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