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March 24, 1962

Use of Gamma Globulin-Reply

Author Affiliations

1086 San Bernardino Rd., Upland, Calif.

JAMA. 1962;179(12):988-989. doi:10.1001/jama.1962.03050120066022

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To the Editor:—  In reply to a question that concerned the prevention of measles, and was answered by John H. Dingle, M.D. (JAMA176:971 [June 17] 1961), I would like to call Doctor Dingle's attention to the recommendations of the American Academy of Pediatrics, as stated in their 1961 Report of the Committee on the Control of Infectious Diseases.On page 22, under the title of Measles, the following is reported: "Measles should be prevented by a large dose of immune serum globulin (gamma globulin) in all infants under 2 or 3 years of age, in chronically ill children, in healthy children whose siblings are ill with other diseases (tuberculosis, pertussis, and rheumatic fever in particular), or when the disease appears in an institution or hospital ward. The dose is 0.25 ml. per kilogram intramuscularly, and should be given as soon as possible after exposure. Gamma globulin should be

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