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October 13, 1962

Thyroid Dysfunction in a Patient with Eosinophilic Gastroenteritis

JAMA. 1962;182(2):195-197. doi:10.1001/jama.1962.03050410091021c

THE PROBLEM OF eosinophilia rarely focuses attention on the gastrointestinal tract. Instead, it brings to mind allergic disorders, parasitic infection, and diseases of the skin and hematopoietic system. Recent hematology texts do not mention the gastrointestinal tract as a cause of increased circulating eosinophils, except in parasitic infection. Eosinophilic granuloma of the gastrointestinal tract only occasionally is associated with an impressive increase in the eosinophilic count.

Recently a patient with gastrointestinal symptoms, eosinophilia, and hypothyroidism was studied at the Peter Bent Brigham Hospital. This unusual case is presented with a brief discussion of eosinophilic gastroenteritis.

Report of a Case

A 65-year-old male carpenter was admitted to the Peter Bent Brigham Hospital in June, 1954, because of malaise, joint pain, shaking chills, fever, and profuse sweating. Penicillin therapy was ineffective and 2 days prior to entry he developed nausea and vomiting.

Medical History.—Bilateral polycystic kidney disease was documented by urograms at