In 100 recent consecutive cases of brain tumors, which were treated surgically by the author, the case mortality was 3%. There were 116 operations, resulting in an operative mortality of 2.6%. All 3 deaths were related to procedures which were essentially biopsies. Of 34 patients with benign tumors, 26 (76%) have returned to their former useful occupations; of 28 with slowly progressive infiltrative tumors, 19 (68%) have returned to work; of 38 with malignant tumors, either primary or metastatic, only 4 (10%) have returned.
Mullan S. Current Mortality of the Surgical Treatment of Brain Tumors: A Study of 100 Consecutive Cases. JAMA. 1962;182(6):601–608. doi:10.1001/jama.1962.03050450001001
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