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July 10, 1967

Dimethyltryptamine, A Do-It-Yourself Hallucinogenic Drug

JAMA. 1967;201(2):143. doi:10.1001/jama.1967.03130020089034

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To the Editor:—  Almost immediately after the hallucinogenic effects of drugs such as mescaline, LSD, and peyote were made known, legal and medical restrictions were applied. Those nonmedical individuals who were determined to experience the hallucinatory effects sought illegal supply channels. As restrictions became more effective, the availability of these substances decreased and the price in the illegal market increased. In accordance with economic principles, substitute drugs were eagerly sought. Such exotic preparations as morning glory seeds and desiccated banana peelings have been used.Up to the present a much more effective though less obvious substance has been neglected. There are only fragmentary reports of the presence of this drug, dimethyltryptamine (DMT), appearing in nonmedical channels and being used for "kicks." It is hoped that a brief discussion of its availability and effects will result in recognition of its dangerous potential and will encourage appropriate control measures.Dimethyltryptamine is found