WHEN epidemiologic consideration is given to the problem of congenital malformations of the heart and great vessels, 3 basic questions arise: (1) how significant is the problem in a community? (2) what is the probability of being born with a cardiovascular defect? and (3) to what extent is life expectancy modified by the presence of a congenital cardiovascular defect?
The first question can be answered by an enumeration of all known cases expressed as a prevalence rate; the second by calculating the incidence of defects at birth; and the third by establishing a life table.
Answers to all 3 questions have been obtained for the City and County of San Francisco and are set down in this report. The data came from 3 major sources: the San Francisco cardiac registry, the city's vital statistics, and estimates of population migration.
Cardiac Registry and Calculation of Prevalence Rate
Since 1946, the names
Mustacchi P, Sherins RS, Miller MJ. Congenital Malformations of the Heart and the Great VesselsPrevalence, Incidence, and Life Expectancy in San Francisco. JAMA. 1963;183(4):241–244. doi:10.1001/jama.1963.63700040001010
Customize your JAMA Network experience by selecting one or more topics from the list below.