Breast cancer is more than one disease. The garden variety of adenocarcinoma with varying degrees of differentiation constitutes the majority of cases, but many types of neoplasms occur. Some neoplasms as colloid carcinoma, medullary cancer with stromal invasion, and intraductal cancer can reach large dimensions with a low incidence of axillary nodal or vascular invasion and carry an improved prognosis.1 A more ominous and less well-understood group are the sarcomas of the breast because of their patterns of spread and their biological behavior.
The host rather than the cancer itself may dominate and express the course of the disease. Inflammatory cancer represents an unusual mode of spread into dermal lymphatics, but may indicate poor host defenses as well as an aggressive tumor. There is a particular concern with the young woman who develops cancer because emotional reactions are understandably heightened —the fear of disfigurement, inability to function completely as
Rubin P. Carcinoma of the Breast: Assorted Problems: Introduction: Special Considerations and Assorted Problems. JAMA. 1967;201(7):527. doi:10.1001/jama.1967.03130070047011
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: