The management of cancer of the male breast presents some interesting contrasts to female breast carcinoma. The relative infrequency of male breast cancer, usually quoted as less than 1% of all breast cancer, is a function of the small amount of mammarian gland tissue in men. The largest, carefully analyzed experience is Treves and Holleb's38 report of 146 cases. General facts worthy of note are that the average age of incidence is 52 years in a range from 24 to 85 years and that the disease is predominant in white men, foreign-born men, and those of Jewish extraction. The detection of a mass in 90% of the patients on presentation would be anticipated with the small amount of adipose tissue in the male breast. Nipple changes occurred in 51% of the cases and a bloody discharge, though encountered in only 16%, was diagnostic of breast cancer if it was
Rubin P. Comment: Male Breast Cancer. JAMA. 1967;201(7):534–535. doi:10.1001/jama.1967.03130070054017
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